GO:0003713 molecular_function transcription coactivator activity
| PAG Title | GO:0003713 molecular_function transcription coactivator activity |
| PAG ID | TAX014772 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator. |
| Species | Homo sapiens |
| Quality Metric Scores | nCoCo Score: 533 |
| Information Content | Rich |
| Other IDs | GO:0003713 |
| Base PAG ID | TAX014772 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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